Composition:
Each gram Doxacil-Vet powder contains Doxycycline HCl BP equivalent to 100 mg Doxycycline.
Indications:
Doxacil-Vet powder is indicated for local & systemic infections of livestock & poultry due to gram-positive & gram-negative Bacteria, Protozoa, Rickettsiae, Mycoplasma etc.
For Poultry: The drug is indicated for the prevention & treatment of Chronic Respiratory Disease (CRD), Infectious Coryza, Colibacillosis, Fowl cholera, Fowl typhoid, Infectious synovitis, Mycoplasmosis & Salmonellosis, Chlamydiosis & Necrotic enteritis etc.
For Large Animal: Doxacil-Vet powder is indicated in the treatment of primary and secondary respiratory infections caused by Pasteurella haemolytica. Pasteurella multocida, Actinobacillus spp. Bordetella bronchoseptica, Streptococcus, Mycoplasma spp.etc. It is also indicated in Pyoderma caused by Staphylococcus; in otitis media, Prostitis, Calf scour etc.
Pharmacology:
Doxycycline is under group of Tetracycline’s which bind to the 30s ribosomal subunit of bacterial ribosome and interfere with the binding of aminoacyl-tRNA to the mRNA molecule in ribosome complex. Thereby interfere with bacterial protein synthesis in growing or multiplying bacteria. Leading to bacteriostatic but higher concentration results bacteriocidal action.
Dosage & Administration:
Poultry: Treatment - 1gram / 2 litre of drinking water for 3-7 days.
For the prevention of early chick mortality: 1 gm / 4 litre of drinking water for 3-4 days.
Large Animal: 15-30 mg. / kg body weight for 3-7 days.
Contraindications & Precaution:
Doxacil-Vet is contraindicated to poultry & animals with known hypersensitivity to any of the tetracyclines. It should not be given to dogs and cats which are pregnant or lactating.
Side effects:
At recommended doses the drug is well tolerated. Side effect is almost nil. Overdosing of Doxycycline to veal calves can occasionally lead to degeneration of heart muscle.
Storage Condition:
Store in a cool & dry place. Protect from sunlight & moisture. Keep out of reach of children.
Withdrawal Period:
For large animal is 8 days & that of Broiler is 4 days.
How Supplied:
10x10 gm, 100 gm & 500 gm pack.
