Product Description
DESCRIPTION:
Necronil TM Vet oral solution is a preparation of Lincomycin and Neomycin.Lincomycin Hydrochloride is a lincosamide antibiotic. It has a bacteriostatic effect mostly on grampositive bacteria. Lincomycin is indicated for the control of necrotic enteritis caused by Clostridium perfringens susceptible to lincomycin.
Neomycin Sulfate is a broad-spectrum antibiotic of the aminoglycoside class. It is active against
gram-positive and gram-negative bacteria like Escherichia coli, Salmonella, Campylobacter,
Pasteurella, Staphylococci and Listeria spp.
COMPOSITION:
Each mL Necronil TM Vet oral solution contains 250 mg Lincomycin Hydrochloride USP equivalent to Lincomycin 250 mg and Neomycin Sulfate BP equivalent to Neomycin 140 mg.
MODE OF ACTION Lincomycin inhibits protein synthesis at the ribosomal level through binding to the 50S ribosomal subunit. After oral administration, lincomycin is absorbed in the gastrointestinal tract and distributed to most organs and tissues. The maximum concentration in the blood is reached in 3- 6 hours after administration. Neomycin Sulfate has a bactericidal effect, inhibits protein synthesis at the ribosomal level through binding to the 30S ribosomal subunit. After oral administration, Neomycin Sulfate is hardly absorbed, the bactericidal effect is mainly provided in the gastrointestinal tract.
INDICATIONS:
Necronil TM Vet oral solution is effective against a wide range of diseases of Poultry mainly
caused by gram- negative & gram-positive bacteria. Such as –
Necrotic enteritis
Bacterial enteritis
Respiratory tract infections
Salmonellosis
Colibacillosis
DOSAGE & ADMINISTRATION:
1 mL / 2-3 liter of drinking water for 3-5 days
As Body Weight:
Neomycin (10 mg/kg b.w./day)
Lincomycin (15-20 mg/kg b.w./day)
Or, as per direction of registered Veterinarian/ Poultry Consultant.
WITHDRAWAL PERIOD:
Meat: 2 days; Egg: 2 days
SIDE EFFECT:
There is no side effect for recommended dosage.
ADVERSE EFFECT:
There is no adverse effect for recommended dosage.
CONTRAINDICATION:
Do not administer to animals hypersensitive to Amino-glycosides and/or Lincosamide.
PRECAUTION:
Can be used only under supervision of a registered veterinarian
Complete full course according to the prescription
Dosage and administration must be as per prescription
STORAGE CONDITION
Store at or below 250 C temperature. Keep away from light and wet place. Keep out of reach of
children.
PRESENTATION:
20 ml, 100 ml & 500 ml
