DESCRIPTION
Doubledex™ S vet bolus is a combination of Triclabendazole & Levamisole which is suitable for small ruminant (Sheep, goat & calf}. Doubledex S vet bolus highly effective against Liver fluke & Roundworm infestation. Doubledex S vet bolus is cattle loving flavored so animal intake easily.
COMPOSITION
Each bolus contains Triclabendazole BP 225 mg & Levamisole Hydrochloride BP equivalent to Levamisole 150 mg.
MODE OF ACTION
Doubledex™ S vet bolus contains two ideal anthelmintics like Triclabendazole & Levamisole. Triclabendazole acts against mature and immature flukes specially against liver flukes (Fascioliosis). It binds to the beta tubulin of the parasites and blocks polymerization of tubulin into
microtubules. The process damages the integrity and transport functions of cells within the parasite and ultimately the parasite dies.
Levamisole is an ideal broad spectrum anthelmintic that acts against respiratory and intestinal round worms. It causes lysis of worms by neuromuscular paralysis. Moreover, it acts as an immunomodulator.
INDICATION
Doubledex™ S vet bolus is a broad spectrum anthelmintic, effective against trematode & nematode worms of cattle, buffalo, sheep/goat etc. Doubledex™ S vet bolus is used for the treatment of acute, sub acute and chronic Fascioliasis (infestation of trematodes) caused by Fasciola gigantica & F. hepatica. Doubledex™ S vet bolus is also used against major stomach,
intestine and respiratory nematodes of ruminants, such as
« Haemonchus spp. * Ostertagia spp. « Cooperia spp.
* Trichostrongylus spp. * Bunostomum spp. « Esophagostomum spp.
* Trichuris spp. Dictyocaulus spp.
DOSAGE & ADMINISTRATION
1 Doubledex™ S vet bolus per 10-19 kg body weight or 19.5 mg per kg body weight.
Doubledex™ S vet bolus can be administered orally through water or by mixing with any feed (e.g. with molasses or by wrapping in a banana leaf) and feeding to the animal.
Or, as per direction of registered veterinarian / consultant.
CONTRAINDICATION
Doubledex™ S vet bolus is contraindicated in animals hypersensitive to
active ingredients.
SIDE EFFECT
Doubledex™ S vet bolus is well tolerated in livestock. At the recommended doses there is no side effect.
DRUG INTERACTIONS
This combination should not be used with Pyrantel, Morantel and Diethylcarbamazine.
OVER DOSAGE
Triclabendazole 16 times and Levamisole 3 times more safe than the recommended dosages.
WITHDRAWAL PERIOD
Milk: 10 days; Meat: 28 days
USES IN PREGNANCY AND LACTATION
There is no effect on pregnant animals if given in recommended dosage. Doubledex™ S vet bolus has no embryonic or teratogenic effect reported in fetus.
PRECAUTION
The animal should be given adequate fluid during and after therapy.
STORAGE CONDITION
Store at or below 25 °C temperature. Keep away from light and wet place. Keep out of reach of children.
PACKAGING
Doubledax™ S vet Bolus: Box containing 5 strips of 6 boli each. Each bolus contains Triclabendazole BP 225 mg and Levamiscle Hydrochloride BP equivalent to Levamisole 150 mg.
