Product Description
Composition
Each ml contains Pheniramine Maleate BP 22.75 mg.
Pharmacology
Pheniramine Maleate acts as H1 receptor antagonist by blocking the binding of histamine to its receptors on bronchi, nerves, vascular smooth muscle etc. and thus inhibits the activation of receptors and corresponding allergic symptoms produced by it. Moreover, Centrally the drug also has some antimuscarinic activity.
Indications
Asta-Vet® is indicated for allergy of diverse origins such as- Cutaneous allergies, Urticaria , Angioneurotic edema, Relief of coughing, Laminitis, Allergic reactions to medicaments, Anaphylactic shock, Insect bites, Eczema, Pruritis, Photosensitization.
Dosage and administration
Route of Administration: IM/IV.
Large animals: 5 to 10 ml or more
Small animals: 0.5 to 1 ml or more
Injection may be repeated after 8-12 hours, if necessary.
The onset of action depends on the mode of administration. Mostly there is an immediate effect on intravenous administration; on intramuscular administration, it takes about 10-20 minutes for the effect to set on. The dosages should be adjusted individually. If possible small doses are given first because it has often been shown that anti-allergic drugs are effective in comparatively small dosage.
Or, as directed by registered Veterinary Physician.
Contraindication
Pheniramine Maleate is contraindicated in animals hypersensitive to it.
Warning and precaution
Pheniramine Maleate should be used with caution in animals with high blood pressure, hyperthyroidism, heart disease, or at risk for urinary obstruction.
Side effects
Common side effects: The most common side effect is sleepiness. Anticholinergic (dry mouth, urinary retention), diarrhea, vomiting, lack of appetite etc. may occur in some cases.
Rare side effects: Anaphylaxis, seizures, tachycardia.
Use in pregnancy & lactation
Use in pregnancy has not been determined. However, risk & necessity should be considered during administration in pregnant & lactating animal.
Drug interaction
With medicine: Pheniramine maleate should be used with caution when given with anticoagulants or central nervous system depressants.
With feed and others: Not known.
Overdose
Overdose can cause CNS stimulation or depression, anticholinergic effects, respiratory depression and death.
Withdrawal time
Meat- Meat must not be consumed up to 7 days after administration of this medicine & Milk- Milk must not be consumed up to 2 days after administration of this medicine.
Storage
Store below 30° C temperature and dry place, protected from light.
Keep all medicines out of reach of children.
Packing
Injection: 10 ml & 100 ml vial.
